Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells

Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areasFocuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cellsFoscuses on the fundamentals and their potential therapeutic and diagnostic applicationsCovers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents INDICE: 1. Interactions of Transition Metal Complexes and Materials with Living Systems of Relevance to Tumour Hypoxia Tracing by Molecular Imaging Techniques2. Protein Binding of Antitumor Metal Complexes3. Immobilized Metal Affinity Chromatography (IMAC) for Metalloproteomics and Phosphoproteomics4. Medicinal Chemistry of Metal N-heterocyclic Carbene (NHC) Complexes5. Luminescent Zinc Complexes as Bioprobes for Imaging Molecular Events in Live Cells6. Antimicrobial Metallodrugs7. Cellular Uptake and Sensing Capability of Transition Metal Peptide Conjugates8. Delivery Systems for CO, NO, and H2S to Explore the Signalling Network of Small-molecule Messengers9. Organoruthenium(II)-Arene Complexes: Structural Building Blocks for Anticancer Drug Discovery10. Luminescent rhenium(I) and iridium(III) complexes for intracellular labeling, sensing, and photodynamic therapy applications

• ISBN: 978-0-12-803814-7
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 360
• Fecha Publicación: 01/03/2017
• Nº Volúmenes: 1
• Idioma: Inglés