Biflavonoids are an important class of plant metabolites offering a range of activities, good availability and relatively low toxicity. Long thought to hold possible therapeutic potential, the recent surge in interest for natural product drug discovery has further highlighted the possibility of using them in the discovery of new drugs, and Biflavonoids: Chemical and Pharmacological Aspects provides a quick reference to the area in a focused manner, to support and encourage further research. Beginning with a focus on the structural features and occurrence of biflavonoids, Chapter 1 reviews key background information including notes on nomenclature and natural distribution. Chapter 2 then goes on to discuss methods for identification and isolation, with separation and purification using various chromatography methods reviewed, followed by identification via UV spectroscopy, NRM spectroscopy and mass spectrometry. Synthesis is the focus of Chapter 3, with a broad range of synthetic methods outlined, before the book concludes in Chapter 4 by describing the biochemical pharmacology of Biflavonoids and their anticancer, antimicrobial, antiviral, anti-inflammatory and analgesic activity. With its discussion of both the underlying chemistry and biological activity of Biflavonoids, Biflavonoids: Chemical and Pharmacological Aspects is a concise guide to this important class of compounds for all those working in the fields of medicinal chemistry and natural products drug discovery. Focused coverage of techniques for the isolation, identification, and synthesis of BiflavonoidsPractical tool for researchers working with these flavonoid compoundsReal-world expertise from the authors provides support for further developments in the growing field of natural product drug discoveryUseful, clear illustrations of key structures throughout the text INDICE: Chapter 1. Structural features and Occurance of Biflavonoids Chapter 2. Isolation and Identification of Biflavonoids Chapter 3. Synthesis of Biflavonoids Chapter 4. Biochemical Pharmacology of Biflavonoids
- ISBN: 978-0-08-101030-3
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 60
- Fecha Publicación: 01/05/2016
- Nº Volúmenes: 1
- Idioma: Inglés