Nanomedicine for Ischemic Cardiomyopathy: Progress, Opportunities, and Challenges

Nanomedicine for Ischemic Cardiomyopathy: Progress, Opportunities, and Challenges

Mahmoudi, Morteza

161,20 €(IVA inc.)

Nanomedicine for Ischemic Cardiomyopathy: Progress, Opportunities, and Challenges provides a historical overview on myocardial infarction and the available clinical and pre-clinical approaches to inhibit correspondence heart failure. Shortcomings of current methods and how nanotechnology can overcome those obstacles in the field is discussed including the limitations of newly developed cell therapy approaches to clinical translation as well as how nanoparticles may overcome crucial issues and facilitate the clinical translation of cell therapy. Biomolecular therapy is also explored as another powerful approach for regeneration of heart tissue including available methods and systematic delivery of biomolecules using nano-carriers to the injured part of myocardium through active targeting. Finally, coverage of major tissue engineering advances for myocardial regeneration, including use of epicardial nano-structured patches for regeneration of injured epicardium and the highly conductive patches for enhancing cross talks between the cardiomyocytes is explored. This concise yet rigorous coverage outlines the innovative and necessary role of nanotechnology in regenerative medicine for cardiac repair allowing researchers, clinicians and nanotechnologists to examine the strengths and limitations of current findings and predict future trends to advance the applications of nanotechnology in cardiovascular biomedical research. Introduces concepts of the unique capacities of cardiac-nanotechnologyPoints to potential and promising applications of engineering nanotechnologies on revolutionizing cell therapy and biomolecular therapy approaches for cardiac regenerationBridges the knowledge gap between cardiologists and cardiac regenerative nanomedicine experts INDICE: 1. Ischemic cardiomyopathy: A Historical Overview2. Nanotechnology: A Historical Overview3. Current Clinical Strategies to Prevent Post Myocardial Infarction Heart Failure4. Use of Nanoparticulate Systems to Salvage Myocardium5. Use of Nanoparticulate Systems to Regenerate Myocardium6. Future trends: Clinicians' Point of View7. Future trends: Nanotechnologists' Point of View

  • ISBN: 978-0-12-817434-0
  • Editorial: Academic Press
  • Encuadernacion: Rústica
  • Páginas: 258
  • Fecha Publicación: 03/02/2020
  • Nº Volúmenes: 1
  • Idioma: Inglés