Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery

Sirtuins play an intricate role in the pathology, progression, and treatment of several disease entities ranging from metabolic disease and diabetes, cancer, cardiovascular disease, immune system dysfunction, to reproductive dysfunction, and aging-related disorders. Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery fills a significant void that provides a unique resource for elucidating the most recent research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities. Scientists, physicians, students and pharmaceutical industry researchers from diverse backgrounds will use this reference as the go-to resource? for both the biology and medical applications that focus upon sirtuins. Details the basic and clinical role of sirtuins and the broad applicability for siruin biology to be targeted for multiple medical disease entities, leading to the development of novel therapeutic treatmentsElucidates the research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entitiesSummarizes the multi-discipline views and publications for this diverse topic, covering cell development, cancer, and metabolism INDICE: 1. Sirtuins, Renal Cancer 2. Sirtuins Cancer, Metabolism, Apoptosis and Autophagy 3. Sirtuins and Leukemia 4. Sirtuins, Cancer, Mitochondrial and Energy Function 5. Sirtuins, Cancer, and Inflammation 6. Sirtuins, Cancer, and NAD pathway 7. Sirtuins and Breast Cancer 8. Sirtuins, Cancer, Metabolism, and Oxidative Stress 9. Sirtuins and Musculoskeketal Cancer 10. Sirtuins, Cancer, and Stem cells 11. Sirtuins in Regulating Immunometabolism

• ISBN: 978-0-12-822467-0
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 350
• Fecha Publicación: 01/02/2021
• Nº Volúmenes: 1
• Idioma: Inglés