Interleukin-1 Mediated Immune Suppression and Resistance to Immunotherapy in Cancer

Interleukin-1 Mediated Immune Suppression and Resistance to Immunotherapy in Cancer summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. It also presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment.The book covers topics about the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers to understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors.It is a valuable source for cancer researchers, clinicians and other members of biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies. Presents a summary in the beginning of each chapter to help readers to find the needed information and understand the content easily Encompasses detailed schematic diagrams and illustrations throughout the content to explain the complex immune mechanisms discussed Discusses future perspectives in all chapters to motivate researchers to work on emerging problems Encloses contributions from internationally reknown experts sharing their experiences on clinics and research INDICE: 1. Source of interleukin-1 in the tumor microenvironment2. Interleukin-1 mediated immune suppression in solid tumor3. Interleukin-1 mediated immune suppression in hematological malignancy4. Mechanism of interleukin-1 mediated immune suppression in the tumor microenvironment5. Interleukin-1 mediated tumor growth and angiogenesis in cancer6. Interleukin-1 mediated resistance to immunotherapy in cancer7. Strategy to overcome interleukin-1 mediated immune suppression and resistance to immunotherapy in cancer

• ISBN: 978-0-12-824273-5
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 200
• Fecha Publicación: 01/12/2022
• Nº Volúmenes: 1
• Idioma: Inglés