Heterocycles in natural product synthesis

Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information,each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particularheterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products is covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry. INDICE: Preface. List of Contributors. Part One Strained Heterocycles in the Synthesis of Natural Products. 1 Aziridines in Natural Product Synthesis (Candice Botuha, Fabrice Chemla, Franck Ferreira and Alejandro Pérez-Luna). 1.1 Introduction. 1.2 Synthesis of Natural Products Containing Aziridine Units. 1.3 Synthesis of Natural Products Involving the Transformation of an Aziridine Moiety. 1.4 Conclusion. References. 2 Azetidine and Its Derivatives (Hidemi Yoda, Masaki Takahashi and Tetsuya Sengoku). 2.1 Introduction. 2.2 Structural Description of Azetidines. 2.3 Synthetic Methodologies for the Formation of Azetidine Rings. 2.4 Synthesis of Mugineic Acids. 2.5 Synthesis of Penaresidins. 2.6 Structural Description of Azetidin-2-ones. 2.7 Synthetic Methodologies for the Formation of Azetidin-2-ones. 2.8 Synthesis of Penicillin. 2.9 Synthesis ofCephalosporin. 2.10 Conclusion. Acknowledgment. References. 3 Epoxides and Oxetanes (Biswanath Das and Kongara Damodar). 3.1 Introduction. 3.2 Epoxides in Natural Product Synthesis. 3.3 Oxetane in Natural Product Synthesis. 3.4 Conclusion. Acknowledgment. References. Part Two Common Ring Heterocycles in Natural Product Synthesis. 4 Furan and Its Derivatives (Alicia Boto and Laura Alvarez). 4.1 Introduction. 4.2 Natural Products Containing the Furan Ring. 4.3 Furan Derivatives as Reagents in the Synthesis of Natural Products. 4.4 Summary. References. 5 Pyran and Its Derivatives (Hideto Miyabe, Okiko Miyata and Takeaki Naito). 5.1 Introduction. 5.2 Application of Pyran Moieties in the Synthesisof Natural Products. 5.3 Conclusion. References. 6 Pyrrole and Its Derivatives (Dipakranjan Mal, Brateen Shome and Bidyut Kumar Dinda). 6.1 Introduction. 6.2 Synthesis of Pyrrole Natural Products. 6.3 Synthesis of Non-pyrrole NaturalProducts from Pyrrole Derivatives. 6.4 Conclusion. Acknowledgments. References. 7 Indoles and Indolizidines (Sarah M. Bronner, G.-Yoon J. Im and Neil K. Garg). 7.1 Introduction. 7.2 Applications of Indoles and Indolizidines in the Synthesis of Natural Products. 7.3 Conclusion. Acknowledgment. References. 8 Pyridine and Its Derivatives (Paula Kiuru and Jari Yli-Kauhaluoma). 8.1 Introduction. 8.2 Application of the Pyridine Moiety in the Synthesis of Natural Products. 8.3 Conclusion. Acknowledgment. References. 9 Quinolines and Isoquinolines(Antonio Garrido Montalban). 9.1 Introduction. 9.2 Application of Quinolines and Isoquinolines in the Synthesis of Natural Products. 9.3 Conclusion. References. 10 Carbazoles and Acridines (Konstanze K. Gruner and Hans-Joachim Knölker). 10.1 Introduction to Carbazoles. 10.2 Total Synthesis of Carbazole Alkaloids. 10.3 Introduction to Acridines. 10.4 Synthesis of Acridines and Acridones.References. 11 Thiophene and Other Sulfur Heterocycles (Krishna C. Majumdar and Shovan Mondal). 11.1 Introduction. 11.2 Synthesis of Natural Products Containing Thiophene. 11.3 Synthesis of Natural Products Containing Other Sulfur Heterocycles. 11.4 Conclusion. Acknowledgments.

• ISBN: 978-3-527-32706-5
• Editorial: Wiley-VCH
• Encuadernacion: Cartoné
• Páginas: 658
• Fecha Publicación: 06/07/2011
• Nº Volúmenes: 1
• Idioma: Inglés