The Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient mouse model frequently used for experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain compared to SD rats both processed in parallel, stained with cresyl violet (Nissl) and placed in 3D using Cinema 4D using flat skull Bregma and Lambda as anatomical landmarks for correct placement in the 3D environment. Each brain structure is illustrated as a volume making it easy to comparable the two rat strains and allow for precise targeting. This enables readers to better calculate co-ordinates to target specific structures for toxin, virus, or cell delivery using stereotaxic surgery. This atlas will serve the needs of any neuroscientist who wishes to work with these mice in experimental and pre-clinical studies and will serve as a valuable resource for the wider research community using nude rats. Features 2D vector-based, color illustrations and 3D reconstructions Contains coronal, sagittal, and horizontal views and Nissl stains Directly compares brain region, shape, size, and relative location in SD rats and the athymic nude rat Allows for easy read-out of coordinates for precise injections using stereotactic surgery Includes 30 µm sections of each mouse strain placed in 3D using Cinema 4D using flat skull Bregma and Lambda as anatomical landmarks for correct placement in the 3D environment INDICE: Introduction (including show case examples mapped in 3D)List of structuresIndex of abbreviationsPart 1: Coronal sectionsPart 2: Horizontal sectionsPart 3: Sagittal sections References
- ISBN: 978-0-323-99740-9
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 150
- Fecha Publicación: 01/06/2023
- Nº Volúmenes: 1
- Idioma: Inglés