Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants, and Their Metabolites

The world?s most comprehensive reference for clinical and forensic toxicologists has once more been extensively updated: 2,000 data sets have been added for a total of 10,430 spectra of potentially harmful substances, including 7,800 from metabolites. In two hardbound volumes, the printed atlas contains a comprehensive listing of full reference mass spectra in order or molecular mass with the structural formula, exact mass, GC retention times and other experimental data that are relevant to the analytical toxicologist. To aid in compound identification, all substances are classified according to their toxicological categories. In addition, volume 1 contains an overview on experimental methods, plus a compound index by name. An electronic database for use with all major mass spectrometers is also available. For details, please visit www.wiley.com/go/databases. INDICE: VOLUME 1. INTRODUCTION. EXPERIMENTAL SECTION. Origin and choice of samples. Sample preparation. GC–MS apparatus. Determination of retention indices. Systematic toxicological analysis (STA) of several classes of drugs and their metabolites by GC–MS. Application of the electronic versions of this handbook using macros or AMDIS. Quantitative determination. CORRELATION BETWEEN STRUCTURE AND FRAGMENTATION. Principle of electron–ionization mass spectrometry (EI–MS). Correlation between fundamental structures or side chains and fragment ions. FORMATION OF ARTIFACTS. Artifacts formed by oxidation during extraction with diethyl ether. Artifacts formed by thermolysis during GC (GC artifacts). Artifacts formed during acid hydrolysis. TABLE OF ATOMIC MASSES. TABLE OF ABBREVIATIONS. REFERENCES. TABLES OF COMPOUNDS. MASS SPECTRA (m/z 30 –. 299). . VOLUME 2. MASS SPECTRA (m/z 300 and higher)

• ISBN: 978-3-527-34287-7
• Editorial: Wiley VCH
• Encuadernacion: Cartoné
• Páginas: 1756
• Fecha Publicación: 19/10/2016
• Nº Volúmenes: 1
• Idioma: Inglés