Chronic Complications of Diabetes Mellitus: Current Outlook and Novel Pathophysiological Insights

Diabetes complications include pathological changes usually related to the vascular system and classical target organs. However, there are also nonclassical complications independent or partially independent from vascular damage that are often overlooked. Chronic Complications of Diabetes Mellitus: Current Outlook and Novel Pathophysiological Insights provides a holistic view of the disease and discuss not only its classical complications but also the under recognized and managed conditions associated with diabetes. Chapters also discuss the advances on the understanding of genomic architecture of diabetes complications and how precision medicine can be used to personalize their management. Endocrinologists, diabetologists, primary care physicians and researchers interested in complications of diabetes mellitus and cutting-edge information on will find this to be a comprehensive tome on the topic. Describes pathophysiology, clinical aspects and treatment of complications of diabetes, including nonclassical complications such as diabetic bone disease and diabetic cardiomyopathy Addresses and discusses the challenges in management of diabetes complications, including prevention and therapeutic strategies Presents up-to-date, thoroughly referenced information for clinicians, researchers and other healthcare providers INDICE: Introductory chapters 1. Overview on chronic complications of diabetes mellitus 2. Epidemiology of chronic complications: A global perspective 3. Molecular mechanisms involved in hyperglycemia-induced cellular damage 4. Vascular calcification in diabetes mellitus: Molecular mechanisms and clinical implications Classical complications 5. Pathogenesis of diabetic atherosclerotic cardiovascular disease 6. Chronic kidney disease in diabetes: Current concepts 7. Diabetic retinopathy: New insights 8. Macular edema: A fearful complication of diabetic eye disease 9. The eye as a mirror of neuronal impairment 10. Diabetic neuropathy: Current issues in diagnosis and prevention Non-classical complications 11. Pathophysiological and clinical aspects of non-classical targets of microangiopathy 12. Diabetic bone disease: Metabolic and microvascular damage 13. Non-alcoholic fatty liver disease: What's before and what are the consequences 14. The diabetic lung 15. Diabetic cardiomyopathy: Pathogenetic mechanisms and clinical consequences 16. Diabetes-related cognitive impairment and dementia in diabetes 17. Cancer in diabetes: Who is who? Outlook in management issues 18. Metabolic memory: what is in it? 19. HbA1c, or glucose variability for causing diabetic complications? 20. Current perspectives on prevention of cardiovascular disease in diabetes 21. Prevention and management of chronic kidney disease in diabetes 22. Heart failure in diabetes: Current clinical management 23. Diabetic eye disease: Novel therapeutic strategies 24. Diabetic foot disease: Recent therapeutic progress

• ISBN: 978-0-323-88426-6
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 300
• Fecha Publicación: 01/02/2023
• Nº Volúmenes: 1
• Idioma: Inglés