This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high–quality articles from the well–known Meyer?s Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with the authors chosen from among the leaders in their respective fields. This volume represents an essential guide for students and researchers seeking an overview of the field. INDICE: Preface ix Volume 1 Part I Basic Biology 1 1 Epigenetic Regulation in Pluripotent Stem Cells 3 Lin Liu and Lingyi Chen 2 Induced Pluripotent Stem Cells 41 Kazutoshi Takahashi and Shinya Yamanaka 3 Naturally Occurring Adult Pluripotent Stem Cells 63 Henry E. Young and Asa C. Black Jr 4 Spermatogonial stem cell (SSCs) system 95 G. Ian Gallicano and Shenglin Chen 5 Stem Cell Dormancy: Maintaining a Reserved Population 119 John M. Perry, Xi C. He, Ryohichi Sugimura and Linheng Li 6 Stem Cells in the Adult Brain: Neurogenesis 133 Michael A. Bonaguidi, Guo–li Ming, and Hongjun Song 7 Embryonic Stem Cells 151 Mahendra Rao Part II Laboratory Methods 175 8 Cardiomyocytes from Human Embryonic Stem Cells 177 Xiu Qin Xu, Manasi Nandihalli, Kar Tong Tan, and William Sun 9 Cloned Mice from Adult Stem Cells 209 Haruko Obokata and Teruhiko Wakayama 10 Cloned Mice from Embryonic Stem Cells 233 Chong Li and Teruhiko Wakayama 11 Haploid Embryonic Stem Cells 255 Ni Hong and Yunhan Hong 12 Muscle Stem Cells: Their Discovery, Properties, and In–Vitro Manipulation 273 Sean McFarland, Ioanna Pagani, and Irina Conboy 13 Nuclear Transfer for Cloning Animals 299 Andras Dinnyes, Xiuchun Cindy Tian, and Bj¨orn Oback 14 Induction of Pluripotent Stem Cells from Umbilical Cord Blood 345 Kejin Hu and Igor Slukvin 15 Development and Renewal of Ventricular Heart Muscle from Intrinsic Progenitor Cells 371 William C.W. Chen and Bruno P´eault Volume 2 Part III Stem Cell Therapy 389 16 Gene Therapy of Genetic Diseases of Blood Cells 391 Gabriela Kuftinec, Jennifer Wherley and Donald B. Kohn 17 Mesenchymal Stem Cells Characteristics, Niches, and Applications for Cell Therapy 429 Joni H. Yl¨ostalo and Thomas J. Bartosh 18 Stem Cells and Parkinson’s Disease 471 Emma Lane, Maria Sundberg, and Jan Pruszak 19 Stem Cell–Based Approaches to Spinal Cord Injury 503 Alexa L. Reeves and Hans Keirstead 20 Therapeutics against Cancer Stem Cells: Targeting the Root of Cancer 521 Kristen M. Smith and Catriona H. M. Jamieson 21 Translating Stem Cells to the Clinic: From Modeling Disease to Cellular Products 573 Emmanuel Nivet, Ignacio Sancho–Martinez, and Juan Carlos Izpisua Belmonte Part IV Stem Cells and Disease 601 22 Cancer Stem Cells 603 Mei Zhang and Jeffrey M. Rosen 23 Normal and Neoplastic Stem Cells 627 Axel Schulenburg and Brigitte Marian 24 Prostate Tissue Stem Cells and Prostate Cancer Progression 655 Collene R. Jeter and Dean G. Tang 25 The Stem Cell Niche and Its Role in Self–Renewal, Aging, and Malignancy 677 Peter Breslin S.J., Andrew Volk and Jiwang Zhang 26 Stem Cells and Colon Cancer 727 Simone Di Franco, Antonina Benfante, Flora Iovino, Sebastiano Bonventre, Francesco Dieli, Giorgio Stassi and Matilde Todaro Index 751
- ISBN: 978-3-527-32925-0
- Editorial: Wiley VCH
- Encuadernacion: Cartoné
- Páginas: 778
- Fecha Publicación: 23/04/2013
- Nº Volúmenes: 1
- Idioma: Inglés