Dynamic combinatorial chemistry: in drug discovery, bioorganic chemistry, and materials science

This book overviews the development and evolution of dynamic combinatorial chemistry (DCC) and fragment-based library methods and how chemists apply them to the problems of lead generation for drug discovery and molecular recognitionin bioorganic chemistry and materials science. Chapters cover basic theory, approaches to binding in proteins and small molecules, molecular recognition, catalyst discovery, click chemistry, SAR by NMR, and analytical chemistry challenges. As such, the book is a valuable resource for chemists building structure libraries and designing compounds.

• ISBN: 978-0-470-09603-1
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 288
• Fecha Publicación: 14/12/2009
• Nº Volúmenes: 1
• Idioma: Inglés