This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on adenosine receptor science, providing insights useful for actual drug discovery/development in neurology and psychiatry areas. Expertise of contributorsSubject including practical drug development from basic science, as translational research tasteStructure of contents focusing on two CNS areas for diseases (neurology and psychiatry) INDICE: Adenosine Receptor Neurobiology: Overview Jiang-Fan Chen, Chien-fei Lee and Yijuang Chern Adenosine Receptor PET Imaging in Human Brain Masahiro Mishina and Kiich Ishiwata An Overview of Adenosine A2A Receptor Antagonists in Parkinson's Disease Peter Jenner Mode of Action of Adenosine A2A Receptor Antagonists as Symptomatic Treatment for Parkinson's Disease Akihisa Mori Adenosine Receptors and Dyskinesia in Pathophysiology Masahiko Tomiyama Clinical/Pharmacological Aspect of Adenosine A2A Receptor Antagonist for Dsykinesia Tomoyuki Kanda and Shin-ichi Uchida Interaction of Adenosine Receptors With Other Receptors from Therapeutic Perspective in Parkinson's Disease Nicolas Morin and Thérèse Di Paolo Effects of the Adenosine A2A Receptor Antagonist on Cognitive Dysfunction in Parkinson's Disease Shin-ichi Uchida, Takako Kadowaki-Horita and Tomoyuki Kanda Clinical Non-Motor Aspect of A2A Antagonist in PD Treatment Masahiro Nomoto, Masahiro Nagai and Noriko Nishikawa Adenosine Receptors and Huntington's Disease Chien-fei Lee and Yijuang Chern Adenosine Receptors and Epilepsy: Established Evidence and Perennial Potential Susan A. Masino, Masahito Kawamura, Jr. and David N. Ruskin Adenosine Receptor Control of Cognition in Normal and Disease Jiang-Fan Chen Adenosine Receptors in Cerebral Ischemia Alessia Melani, Anna Maria Pugliese, and Felicita Pedata Roles of Adenosine and its Receptors in Sleep-Wake Regulation Zhi-Li Huang, Ze Zheng and Wei-Min Qu Involvement of Adenosine A2A Receptors in Depression and Anxiety Koji Yamada, Minoru Kobayashi and Tomoyuki Kanda The Adenosine Neuromodulation System in Schizophrenia Daniel Rial, Diogo R. Lara and Rodrigo A. Cunha
- ISBN: 978-0-12-801022-8
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 242
- Fecha Publicación: 01/09/2014
- Nº Volúmenes: 1
- Idioma: Inglés