Nitric Oxide in Health and Disease: Therapeutic Applications in Cancer and Inflammatory Disorders

Nitric Oxide in Health and Disease: Therapeutic Applications in Cancer and Inflammatory Disorders presents updated information on the chemistry, signaling of newly derived therapeutic nitric oxide donors/inhibitors, and their complexes in liposomes or nanospheres in both pre-clinical and clinical activities. It discusses many examples of research related to the application of novel therapeutic compounds that focus on a chemical, nitric oxide, and their applications that have been shown to exert significant therapeutic activities against various resistant cancers unresponsive to current treatments, and different inflammatory diseases which continue to require novel treatments. It is a valuable resource for cancer researchers, oncologists, graduate students, and researchers from medical and biomedical fields who want to know more about NO and its therapeutic applications in cancer and inflammatory diseases. Provides updated reviews on the chemistry, signaling of newly derived therapeutic nitric oxide (NO) donors/inhibitors and their complexes in liposomes or nanospheres in both pre-clinical and clinical activities Discusses the application of NO in monotherapy or in combination with conventional therapies in a variety of cancers and inflammatory Encompasses real-world examples of recent research related to NO and cancer so that readers INDICE: Section 1: General properties of NO/metabolites in human diseasesSection 2: Development of novel NO donors/inhibitors and NO complexes: properties, cell signaling, synergy Section 3: Pharmacokinetics of NO donors/inhibitors in animal models and toxicities Section 4: Red-Ox signaling and modification of proteins. Characterization of their modified functions  Section 5: Therapeutic applications of NO donors/inhibitors in non-cancer related human diseases Section 6: Therapeutic applications of NO donors/inhibitors in various cancersConcluding remarks and future perspectives

• ISBN: 978-0-443-13342-8
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 300
• Fecha Publicación: 01/04/2023
• Nº Volúmenes: 1
• Idioma: Inglés