Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies

Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines the recent continuous advancements that are one of the defining characteristics of pharmaceutical technology. The pharmaceutical industry is highly dynamic and rapidly expanding. This field of study demands a variety of amplified efforts for developing pharmaceutical processes and formulation strategies. This book discusses common formulation strategies including the use of tools for statistical formulation optimization, Quality by design (QbD), and process analytical technology as well as exploring the uses of various pharmaceutical biomaterials including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. Recent developments have resulted in the development of technologies including prodrugs, coating, microencapsulation, nanotechnology, allowing the design of newer, effective drug delivery and targeting systems and devices. Multiple common modes of drug administration, including oral drug delivery, transdermal drug delivery, buccal drug delivery, ocular drug delivery, gastroretentive drug delivery, colon-targeted drug delivery, brain-targeted drug delivery, and bone-targeted drug delivery, can be accomplished using implants, gels, liposomes, iontophoresis, ultrasonic, or MEMS. This book addresses these rapid advancements by providing a thorough understanding of the pharmaceutical processes and formulation development and explorations and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies will be useful to a variety of readers including Pharmacy, Biotechnology, and Bioengineering. Provides extensive information and analysis on recent advancements in the field of pharmaceutical technologyIncludes contributions from global leaders and experts in academia, industry and regulatory agenciesUses high quality illustrations, flow charts, and tables to explain concepts and texts to the readers along with practical examples and research case studies INDICE: 1. Natural polymers as useful pharmaceutical excipients2. Synthetic and semi-synthetic polymers for pharmaceutical applications 3. Engineered plant gums as improved pharmaceutical applications 4. Grafted polysaccharides as advanced pharmaceutical excipients5. Smart polymers in advanced drug delivery 6. Design  and development of dosage forms: Influences of anatomy and administration routes 7. Effective formulation development strategies for poorly soluble drugs8. Formulation strategies to improve the bioavailability of poorly absorbed drugs9. Drug transport across the biological barriers present in human body10. Pharmaceutical coating processes11. Process analytical technology (PAT) tools: Uses in pharmaceutical manufacturing12. Pharmaceutical product development: A quality by design (QbD) approach13. Polymeric gels as drug delivery vehicles 14. Nanoparticles as effective drug delivery carriers 15. Iontophoretic drug permeation enhancement techniques 16. MEMS based drug delivery systems17. Ultrasonic drug delivery devices 18. Recent developments in siRNA delivery strategies

• ISBN: 978-0-12-820043-8
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 870
• Fecha Publicación: 03/08/2020
• Nº Volúmenes: 1
• Idioma: Inglés