Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and the biotechnology industry in extensive detail to understand the field and develop high quality products. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers' biocompatibility, biodegradability, economic extraction and ready availability. These natural materials are renewable if grown sustainably, and they can tender incessant supply of raw materials. Amongst these natural polymers, Alginates are considered excellent excipients because of their non-toxic, stable and biodegradable properties, and can be used in a variety of applications in pharmaceuticals, medical diagnostic aids and material science. Several innovations have been made on applications of alginate in drug delivery and biomedicines including in liquid gels, powders, beads, films, tablets, capsules, microspheres, microparticles, nanoparticles, nanosponges, nanofibrils and nanocomposites. To fully utilize and harness the potential of alginates, a thorough understanding of the synthesis, purification, and characterization of alginates and their derivatives needs to be is needed. This book collects in a single volume all relevant information on alginates in health care including recent advances in the field. Alginates in Drug Delivery is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences. Provides a single source examining the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fieldsIncludes high quality illustrations along with practical examples and research case studiesContains contributions by global leaders and experts from academia, industry and regulatory agencies, who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields INDICE: 1. Introduction to alginates as drug delivery excipient 2. Alginates hydrogels for drug delivery applications 3. Alginates nanoparticles in drug delivery 4. Ionotropically gelled alginate-based multiple-unit matrices in sustained drug release 5. Physically and chemically modified alginates in drug delivery 6. Grafted alginates in drug delivery 7. Alginate-based interpenetrating polymer networks for sustained drug release 8. Biocomposites of alginates in drug delivery 9. Alginate-inorganic composite matrices as drug releasing carriers 10. Buoyant particles of alginates in floating drug delivery 11. Alginate-based hydrogel membranes for drug releasing in wound healing 12. Alginate-based scaffolds for drug delivery in tissue engineering
- ISBN: 978-0-12-817640-5
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 312
- Fecha Publicación: 01/02/2020
- Nº Volúmenes: 1
- Idioma: Inglés