Disease Pathways: An Atlas of Human Disease Signaling Pathways

Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void in the literature on illustrated reviews of well-documented and understood mechanisms of human diseases on both cellular and molecular levels. It is built from the powerful knowledgebase of biological relationships with analytical and visualization tools from Pathway StudioT, Elsevier's proprietary commercial software that harnesses text mining technology to process a vast collection of published data, extracting biological terms, concepts and relationships. The core content is gleaned from 10,000+ total journals, 1,700+ full-text journals, 25M+ PubMed Abstracts and 200,000+ clinical trials. The atlas covers 30 human diseases and focuses on a brief summary of a disease, including key aspects of etiology and clinical picture, a short glossary, and images of the disease signaling pathways with narration and references. The book provides the reader with detailed information on the basic concept of disease signaling pathways on a highly scientific level, while simultaneously keeping the presentation clear and simple. This is a must-have for general biologist, biochemists, students, and medical workers. In addition, readers who require information to understand cellular and molecular mechanisms of human diseases could also find it useful. Designed as an atlas with basic reviews and summaries on cell signaling in the context of human diseasesHighlights detailed scientific information on the basic concept of disease signaling pathways with simple and clear presentationsVisualizes cell signaling with powerful images of the causes of disease pathology, thus making information more intuitiveIncludes clear, full-color illustrations of the pathways and networks that determine biological function INDICE: 1. Part One 1. Introduction to the cell signaling biochemistry and proteomics 2. System biology and signaling pathways 3. Complexity of molecular mechanisms of human diseases 2. Part Two 1. Cardiovascular Diseases 2. Dermatological Diseases 3. Endocrine and Metabolic Diseases 4. Intestinal Diseases 5. Musculoskeletal System Diseases 6. Neurological Diseases 7. Obstetrics and Gynecology Diseases 8. Ophthalmology/Eye Diseases 9. Otolaryngological Diseases 10. Respirator and Pulmonology Diseases 11. Nephrology Diseases 3. Part Three 1. Methods of using intracellular maps for diagnosis of diseases in personalized medicine 2. Conclusion

• ISBN: 978-0-12-817086-1
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 350
• Fecha Publicación: 01/08/2019
• Nº Volúmenes: 1
• Idioma: Inglés