INDICE: Basic Concept of Development and Practical Application of Animal Models for Human Diseases.- Humanized SCID mouse models for biomedical research.- NOD/Shi-scid IL2 rgnull (NOG) mice more appropriate for a humanized mouse model.- Humanizing Bone Marrow in Immune Dificient Mice.- The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in the NOD-SCID/IL2rgnullmice.- Antigen specific antibody production of human B cellsin NOG mice reconstituted with human immune system.- Humanized Immune System (HIS) mice as a tool to study human NK cell development.- Human T cell development and HIV infection in Human Hemato-Lymphoid System Mice.- Humanized mice for human retrovirus infection.- Functional and Phenotypic Characterization of the Humanized BLT Mouse.- Novel metastasis models of human cancer in NOG mice.- In vivo imaging in humanized mice.- Subject index.
- ISBN: 978-3-540-75646-0
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 199
- Fecha Publicación: 01/03/2008
- Nº Volúmenes: 1
- Idioma: Inglés