Angiotensin: From the Kidney to Coronavirus, a new volume in the Molecular Mediators in Health and Disease series, presents the communication role of the hormone in both health and disease states. Beyond the most common conditions, the book also explores the role of Angiotensin in infectious diseases, like COVID-19. Sections provide background to its discovery and role in homeostasis, focus on molecular biology aspects, including genetics and measurements of its associated proteins, describe the specific actions of angiotensin in normal physiology with different organ systems, survey different classes of drugs that act on the Renin-angiotensin-aldosterone system, cover non-angiotensin II peptides, and more. The final part of the book is dedicated to angiotensin's role in disease states, making this the ideal reference for researchers in life sciences interested in understanding the physiological role of Angiotensin in a complete fashion. Research physicians will also benefit from the book's complete coverage of organ systems and diseases where Angiotensin plays a key role. Covers the traditional disorders related to Angiotensin and new findings like its role in infectious diseases like COVID-19 Offers an overview of all important aspects of angiotensin, from discovery to clinical application, from physical and chemical properties to the physiological/cellular interaction Expands on the role of angiotensin beyond the individual system the researcher is focusing, providing a comprehensive coverage of the additional effects at cell, tissue, organ, and system levels INDICE: Part I - Introduction to angiotensins History of Angiotensin Angiotensin in Normal Biology Part II - Molecular biology of angiotensins Genes involved in the RAAS Measurement of angiotensins Part III - Angiotensin in organ function Angiotensin in blood vessels Angiotensin in the Kidney Angiotensin in BrainAngiotensin in the Eye Angiotensin in reproductive organs (e.g. testes, ovaries, sex-specificity)Angiotensin in the carotid bodyAngiotensin and aldosteroneAngiotensin and the LungPart IV - Angiotensin pharmacology Angiotensin-converting enzyme inhibitors (ACE-I) The angiotensin receptor blockers (ARB) Renin-inhibitors Angiotensin II as a therapeutic agentPart V - Non-angiotensin II peptides Non-angiotensin II peptidesPart VI - Angiotensin in non-mammalian biology Angiotensin in other areas of biologyAngiotensin in insects and other non-mammalian organisms Part VII - Angiotensin in Disease Adenomas of the renin angiotensin aldosterone systemAngiotensin and cancer Angiotensin and Psychiatry Angiotensin and infectious disease
- ISBN: 978-0-323-99618-1
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 450
- Fecha Publicación: 01/02/2023
- Nº Volúmenes: 1
- Idioma: Inglés