Neuroimaging in Parkinson's Disease and Related Disorders discusses the advances of molecular, structural and functional Neuroimaging techniques that have helped to investigating aetiology, pathophysiology, and effects and complications of novel therapies in Parkinson's and related disorders. There has been an explosion of research in Neuroimaging methodologies over the past 5 years and this book provides a comprehensive overview of all of the recent new technologies and research in the field. This book discusses the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson's disease and related disorders. It helps the reader understand the in vivo pathology and pathophysiology Parkinson's disease and in a number of related disorders. Also discussed is the association between clinical symptoms and clinical progression, and molecular, structural, functional changes in the brain of patients with Parkinson's disease and related disorders. Comprehensive overview of biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson's disease and related disorders Helps readers understand the in vivo pathology and pathophysiology Parkinson's disease and in a number of related disorders Discusses the association between clinical symptoms and clinical progression, and molecular, structural, functional changes in the brain of patients with Parkinson's disease and related disorders INDICE: Section I. Introduction 1. Parkinson's disease and related disorders: The pursuit for reliable readouts and the role of neuroimaging 2. Advances Magnetic Resonance Imaging 3. Advances in Molecular Imaging Methodology Section II. Clinical Applications in Parkinson Disease 4. Dopaminergic molecular imaging in familial and idiopathic PD 5. Serotonergic molecular imaging in familial and idiopathic PD 6. Other systems PET and SPECT imaging in familial and idiopathic PD 7. Structural MRI in familial and idiopathic PD 8. Functional MRI in familial and idiopathic PD 9. Molecular imaging in Prodromal PD Section III. Clinical Applications in Lewy Body Dementias 10. Molecular Imaging evidence in favour or against PDD & DLB overlap 11. MR Imaging in PD-MCI, PDD & DLB Section IV. Clinical Applications in Atypical Parkinsonian Disorders 12. Neuroimaging in MSA 13. Neuroimaging in PSP 14. Neuroimaging in CBS Section V. Clinical Applications in Other Movement Disorders 15. Molecular imaging in Huntington's Disease 16. Magnetic Resonance Imaging in Huntington's disease 17. Neuroimaging in Essential Tremor 18. Neuroimaging in Restless leg syndrome 19. Neuroimaging in Dystonia 20. Demyelination Syndromes and Movement Disorders Section VI. Conclusions 21. The Future of Neuroimaging and the Application for Robust Measures in Clinical Trials
- ISBN: 978-0-12-821651-4
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 500
- Fecha Publicación: 01/11/2022
- Nº Volúmenes: 1
- Idioma: Inglés