Pain is the number one reason that people seek medical attention but pain is still under- and poorly-treated world wide. The purpose of this book is to give an up to date picture of what causes pain, how pain becomes chronic and what pharmacological targets might be manipulated to alleviate acute and chronic pain. The book will cover a wide array of topics from gene polymorphisms to voltage-gated ion channels moving from cellular biology to whole animal physiology. written by future leaders in the pain fieldcovers a wide range of targetscontains provocative ideas about the future direction of the pain field. INDICE: Regulation of gene expression and pain states by epigenetic mechanisms Sandrine Geranton Chemotherapy-induced peripheral neuropathy Jill FehrenbacherDorsal horn AMPA receptor trafficking in chronic inflammatory pain Yuanxiang TaoThe contribution of mitochondria to sensory processing and pain Sarah Flatters Role of anti-inflammatory factors in the regulation of persistent pain Camilla SvennsonTranslation control of chronic pain Ohannes Melemedjian Sensory TRP Channels: The Key Transducers of Nociception D. P. MohapatraModulation of Voltage-gated Na+/K+ Channels in Inflammatory and Neuropathic Pain D. P. MohapatraNon-neuronal central mechanisms: glia and immune response Alfonso Romero-SandovalPeripheral Scaffolding and Signaling Pathways in Inflammatory painNathan JeskePain mechanisms and their therapeutic potential Amol Patwardhan Dendritic Spine Dysgenesis in Neuropathic Pain Andrew TanmiRNA biology and pain Seena AjitCRMP-2, a novel biological target for chronic pain Rajesh KhannamGluRs head to toe in pain Ben KolberSynaptic inhibition and disinhibition in the spinal dorsal horn Steve PrescottStress and Chronic Pelvic Pain Julie ChristiansonAcid Sensing ion channels in pain and headache Greg DussorMolecular mechanisms of nociceptive memory? Ted Price Dietary influence on pain via the immune system Robert SorgeContribution of mechanosensitive ion channels to somatsensation Reza Sharif Naeini
- ISBN: 978-0-12-801389-2
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 550
- Fecha Publicación: 01/02/2015
- Nº Volúmenes: 1
- Idioma: Inglés