Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory ad test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria. An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. Genetic Toxicology Testing: A Laboratory Manual is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own. Offers practical and consistent guidance on the most commonly-performed tests and procedures in a genetic toxicology labDescribes standard genetic toxicology assays, their methodology, reagents, suppliers, and analysis of their resultsIncludes guidance on general approaches: formulation for in vitro assays, study monitoring, and Good Laboratory Practice (GLP)Serves as an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own lab INDICE: 1. Introduction2. Laboratory Design and Safety3. Formulation4. Bacterial Mutation Test5. The Mouse Lymphoma TK Assay6. In Vitro Micronucleus7. In Vitro Chromosome Aberration8. Rodent Micronucleus9. Rodent Chromosome Aberration10. Comet Assay11. PigA Mammalian Erythrocyte Mutation
- ISBN: 978-0-12-800764-8
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 304
- Fecha Publicación: 01/06/2016
- Nº Volúmenes: 1
- Idioma: Inglés