Emery and Rimoins Principles and Practice of Medical Genetics and Genomics: Foundations

For decades, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics into medical practice. With nearly 5,000 pages of detailed coverage, contributions from over 250 of the world's most trusted authorities in medical genetics, and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for medical students, residents, physicians, and researchers involved in the care of patients with genetic conditions. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. This first Volume, Foundations, summarizes basic theories, concepts, research areas, and the history of medical genetics, providing a contextual framework for integrating genetics into medical practice. In this new edition, clinically oriented information is supported by full-color images and expanded sections on the foundations of genetic analytics, NGS, and therapeutics. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics: Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers. Introduces genetic researchers, students, and health professionals to basic theories, concepts, research areas, and the history of medical genetics, offering a contextual framework for integrating genetics into medical practiceCompletely revised and up-to-date, this new edition highlights traditional approaches and new developments in the field of medical genetics - including cancer genetics, genomic technologies, genome and exome sequencing, prenatal diagnosis, public health genetics, genetic counseling, and single-cell analysis for diagnosisIncludes color images supporting identification, concept illustration, and method processingFeatures contributions by leading international researchers and practitioners of medical geneticsA robust companion website offers lecture slides, image banks, and links to outside resources and articles to stay up-to-date on the latest developments in the field INDICE: 1. History of Medical Genetics2. Medicine in a Genetic Context3. Precision Medicine4. Nature and Frequency of Genetic Disease6. Genome and Gene Structure7. Genome Structure8. Epigenetics9. Human Gene Mutation in Inherited Disease: Molecular Mechanisms and Clinical Consequences10. Genes in Families11. Analysis of Genetic Linkage12. Chromosomal Basis of Inheritance13. Mitochondrial Medicine: The Mitochondrial Biology and Genetics of Metabolic and Degenerative Diseases, Cancer, and Aging14. Mitochondrial Biology - split of above chapter15. Mitochondrial Disorders - split of above chapter16. Multifactorial Inheritance and Complex Diseases17. Immunologic Disorders: Autoimmunity: Genetics and Immunologic Mechanisms18. Population Genetics19. Pathogenetics of Disease20. Twins and Twinning21. The Biological Basis of Aging: Implications for Medical Genetics22. Pharmacogenetics and Pharmacogenomics

• ISBN: 978-0-12-812537-3
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 448
• Fecha Publicación: 01/11/2018
• Nº Volúmenes: 1
• Idioma: Inglés