The Science of Hormesis in Health and Longevity

The Science of Hormesis in Health and Longevity provides a comprehensive review of mild stress-induced physiological hormesis and its role in the maintenance and promotion of health. Coverage includes the underlying mechanisms of hormesis, including details of stress-response signaling, an enriched environment, positive challenges and dose-response mechanisms, amongst others. Research from top experts is presented to provide suggestions for developing novel therapeutic strategies, along with lifestyle interventions to promote health and homoeostasis. Researchers in aging and physiology, gerontologists, clinicians and medical students will find this a valuable addition for their work. Provides a comprehensive, scholarly review of the current state of hormesis in physiology, health, disease and agingIncludes multiple perspectives and in-depth analysis by top experts involved in cutting-edge research to provide developing, novel therapeutic strategies, as well as lifestyle interventionsOffers a clear understanding of hormesis' underlying mechanisms, including details of stress-response signaling, an enriched environment, positive challenges, dose-response mechanisms, and more INDICE: Section 1: HISTORY, TERMINOLOGY AND CONCEPTS 1. The revival of hormesis 2. Hopes and challenges for hormesis 3. Hormesis or adaptive homeostasis 4. Evolutionary adaptation under environmental stress Section 2: STRESSORS AND STRESS RESPONSES 5. Oxidative stress 6. Metabolic stress 7. Genotoxic stress 8. Inflammatory and pathogen stress 9. Neuronal stress 10. Food restriction and its mimetics 11. Intermittent fasting as a hormetin 12. Mental stress 13. Aging and decreased resistance to multiple stresses Section 3: HORMETIC MODULATION OF AGEING 14. Biological basis of ageing and its modulation thoguh hormesis 15. Nutritional hormesis in a modern environment 16. Exercise as a paradigm for hormesis for health and longevity 17. Injuries can prolong lifespan in Drosophila melanogaster males 18. Intellectually and socially complex environment on human resilience in ageing 19. Interactions with technology as a cognitive anti-ageing hormetic stimulus Section 4: HORMESIS AGAINST DISEASES 20. Radiation hormesis in disease prevention and treatment 21. Reduced Ovarian Cancer Incidence in Women Exposed to Low Dose Ionizing Background Radiation 22. Mitochondrial challenges in Cardiorenal Syndrome 23. Hormesis in Cholestatic Liver Disease; Preconditioning with Low Bile Acid 24. Adaptive preconditioning in neurological diseases - therapeutic insights from proteostatic perturbations 25. Protecting neurons against cellular stress in Parkinson disease 26. Phyto-hormetins in a clincal setting Section 5: FUTURE OF HORMETICS 27. Hormetin products in cosmetics and food supplements 28. Hopes and challenges for hormesis

• ISBN: 978-0-12-814253-0
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 352
• Fecha Publicación: 01/10/2018
• Nº Volúmenes: 1
• Idioma: Inglés