Translational Autoimmunity: Autoimmune Disease Associated with Different Clinical Features

Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases.  The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Covers clinical aspects of autoimmunity and translational immunology studies in autoimmunity in different clinical settings Meets the needs of basic scientists, clinicians, translational scientists and industry partners Supported by a systematic appraisal of the most recent evidence INDICE: 1. Introduction on autoimmunity and associated conditions2. Crosstalks between autoimmunity and cancer3. Autoinmmunity regulation within the tumor microenvironment4. Mechanisms of immune tolerance breakdown in inborn errors of immunity5. Autoimmunity in classic combined immunodeficiencies6. Selective IgM deficiency and autoimmunity7. Evans syndrome at crossroads of immune deficiency and immune dysregulation8. Autoimmunity and HIV infection9. M. paratubeculosis (MAP) as a zoonotic pathogen that provokes autoimmunity via molecular mimicry10. Autoimmune diseases and metabolic disorders: molecular connections and potential therapeutic targets11. Autoimmunity and infertility12. Autoimmunity and its influence on human male infertility- A multi parameter approach13. Autoimmunity and its correlation to inflammatory vascular diseases14. Autoimmunity in atherosclerosis15. Allergy and autoimmunity: share of genetics and environment16. Asthma and autoimmunity17. Autoimmunity in interstitial lung diseases18. Role of autoimmunity in the pathogenesis of chronic obstructive pulmonary disease and pulmonary emphysema19. Autoinflammation and cystic fibrosis20. Autoimmunity and psychosis21. Autoimmunity and chronic urticaria22. Translational immunology in immune mediated oral diseases23. Oxidative stress in oral autoimmune disorders

• ISBN: 978-0-323-85415-3
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 402
• Fecha Publicación: 15/04/2022
• Nº Volúmenes: 1
• Idioma: Inglés