Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue. Biointegration of medical implant materials, Second Edition, provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. This new edition is updated and expanded to include the very latest developments biointegratin, including a new section on tissue regeneration. Part one discusses soft tissue integration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews tissue regeneration with a range of applications from cardiac tissue regeneration to dental tissue regeneration. Drug delivery is reviewed in Part 3 with topics including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part four covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering. With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integrationDiscusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstructionExpanded to include new information on a variety of tissue regeneration techniques and applications INDICE: 1. Biointegration: an introduction Part 1 Soft tissue biointegration 2. Biocompatibility of engineered soft tissue created by stem cells 3. Replacement materials for facial reconstruction at the soft tissue-bone interface 4. Corneal tissue engineering 5. Tissue engineering for small-diameter vascular grafts 6. Stem cells for organ regeneration Part 2 Tissue Regeneration 7. Regeneration of organs 8. Cardiac Regeneration 9. Tissue based products 10. Tendon regeneration 11. Dental regeneration Part 3 Drug delivery 12. Materials facilitating protein drug delivery and vascularisation 13. Inorganic nanoparticles for targeted drug delivery 14. Alginate-based drug delivery devices 15. Functionalised nanoparticles for targeted drug delivery Part 4 Design considerations 16. Biocompatibility of materials and its relevance to drug delivery and tissue engineering 17. Mechanisms of failure of medical implants during long-term use 18. Rapid prototyping in biomedical engineering: structural intricacies of biological materials
- ISBN: 978-0-08-102680-9
- Editorial: Woodhead Publishing
- Encuadernacion: Rústica
- Páginas: 450
- Fecha Publicación: 01/09/2019
- Nº Volúmenes: 1
- Idioma: Inglés