This is a comprehensive tutorial reference to the foundational science and evolving clinical impact of our rapidly expanding understanding of the blood brain and blood-spinal cord brain barrier (BBB/BSCB). This comprehensive reference begins with a detailed introduction to the Anatomy and Physiology of the BBB/BSCB providing a solid foundation for what follows. The next section focuses specifically on neuropharmacology and BBB/BSCB and then to drug delivery including detailed coverage of nanoparticles (risk and potential for drug delivery). The final section covers the effects of drugs and narcotics on the BBB/BSCB and the alteration of the BBB/BSCB in disease states including Alzheimer, Huntington and Parkinson. This will be a definitive reference on our current understanding of the BBB/BSCB and the impact of the BBB/BSCN on the brain and central nervous system in health and disease. This combination on basic science and application to clinical concerns will be of great interest to all neuroscience, clinical neurology, and psychiatric researchers especially those involved in drug delivery. * A comprehensive reference introducing the basic science and possible application of the latest research on the blood-spinal cord brain barrier. * Focused on the impact of the BBB/BSCB on health and disease of the brain and the central nervous system. * Includes detailed chapters on nanoparticles, neurodegenerative diseases and psychostimulants INDICE: Section I. Anatomical structure and functions of the blood-brain barrier Section II. Physiology of the blood-brain barrier Section III. Neuropharmacology of the Blood-CNS Barrier Section IV. Drug delivery across the BBB Section V. Nanoparticles and the Blood-CNS barrier Section VI. Psychostimulants and the blood-brain barrier Section VII. Stress and Affective Disorders and the blood-CNS barrier Section VII. Cardiac Arrest and the blood-CNS barrier Section VII. Neuropathic Pain and the blood-CNS barrier Section VIII. Neuropathology and the Blood-brain barrier Section IX. Blood-brain barrier in Neurotrauma Section X. Comorbidity factors in neurological disease and the Blood-brain barrier Section XI. Neurodegenerative diseases and the blood-brain barrier Section XI. Blood-brain barrier in Alzheimer's Disease
- ISBN: 978-0-12-800933-8
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 864
- Fecha Publicación: 13/12/2015
- Nº Volúmenes: 1
- Idioma: Inglés
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