G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes. Covers a broad range of topics related to GPCR activation and signaling Covers several receptor systems with an emphasis on emerging paradigms Covers different processes and model systems with a focus on GPCRs INDICE: Preface Arun K. Shukla 1. GPCR heteromers as therapeutic targets Peter McCormick 2. Computational and experimental approaches to probe GPCR activation and signaling Dorota Latek 3. Adrenergic receptors in breast cancer Isabel Alicia Luthy 4. Jackson C. Bittencourt 5. Tools for adapting to a complex habitat: G-protein coupled receptors in Trichoderma Monika Schmoll 6. to GPCR signaling in etiology of chronic pain and therapeutics Prem N. Yadav 7. Crosstalk between neurons and glia through G-protein coupled receptors: insights from Caenorhabditis elegans Kavita Babu 8. Cardiovascular GPCR Regulation by Regulator of G Protein Signaling Proteins Anastasios Lymperopoulos 9. The interaction, mechanism and function of GPR158-RGS7 cross-talk Laurie Sutton 10. Taste GPCRs and their ligands Masha Y. Niv
- ISBN: 978-0-323-99431-6
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 300
- Fecha Publicación: 01/12/2022
- Nº Volúmenes: 1
- Idioma: Inglés