Principles of Genetics is one of the most popular texts in use for the introductory course. It opens a window on the rapidly advancing science of genetics by showing exactly how genetics is done. Throughout, the authors incorporate a human emphasis and highlight the role of geneticists to keep students interested and motivated. The seventh edition has been completely updated to reflect the latest developments in the field of genetics. Principles of Genetics continues to educate today s students for tomorrow s science by focusing on features that aid in content comprehension and application. INDICE: Chapter 1 The Science of Genetics .The Personal Genome .An Invitation .Three Great Milestones in Genetics .DNA as the Genetic Material .Genetics and Evolution .Levels of Genetic analysis .Genetics in the World: applications of Genetics to human Endeavors .Chapter 2 Cellular Reproduction .Cells and Chromosomes .Mitosis .Meiosis .Life Cycles of Some Model Genetic Organisms .Chapter 3 Mendelism The Basic Principles of Inheritance .Mendel s Study of heredity .Applications of Mendel s principles .Testing Genetic hypotheses .Mendelian principles in human Genetics .Chapter 4 Extensions of Mendelism .Allelic Variation and Gene Function .Gene Action: From Genotype to Phenotype .Inbreeding: Another Look at Pedigrees .Chapter 5 The Chromosomal Basis of Mendelism .Chromosomes .The Chromosome Theory of Heredity .Sex–Linked Genes in Humans .Sex Chromosomes and Sex Determination .Dosage Compensation of X–Linked Genes .Chapter 6 Variation in Chromosome Number and Structure .Cytological Techniques .Polyploidy .Aneuploidy .Rearrangements of Chromosome Structure .Chapter 7 Linkage, Crossing Over, and Chromosome Mapping in Eukaryotes .Linkage, Recombination, and Crossing Over .Chromosome Mapping .Cytogenetic Mapping .Linkage Analysis in Humans .Recombination and Evolution .Chapter 8 The Genetics of Bacteria and Their Viruses .Viruses and Bacteria in Genetics .The Genetics of Viruses .The Genetics of Bacteria .Mechanisms of Genetic Exchange in Bacteria .Chapter 9 DNA and the Molecular Structure of Chromosomes .Proof That Genetic Information Is Stored in DNA and RNA .The Structures of DNA and RNA .Chromosome Structure in Viruses and Prokaryotes .Chromosome Structure in Eukaryotes .Special Features of Eukaryotic Chromosomes .Chapter 10 Replication of DNA and Chromosomes .Basic Features of DNA Replication In Vivo .DNA Replication in Prokaryotes .Unique Aspects of Eukaryotic Chromosome Replication .Chapter 11 Transcription and RNA Processing .Transfer of Genetic Information: The Central Dogma .The Process of Gene Expression .Transcription in Prokaryotes .Transcription and RNA Processing in Eukaryotes .Interrupted Genes in Eukaryotes: Exons and Introns .Removal of Intron Sequences by RNA Splicing .Chapter 12 Translation and the Genetic Code .Protein Structure .Genes Encode Polypeptides .The Components of Polypeptide Synthesis .The Process of Polypeptide Synthesis .The Genetic Code .Codon–tRNA Interactions .Chapter 13 Mutation, DNA Repair, and Recombination .Mutation .The Molecular Basis of Mutation .Mutagenesis .Complementation Test .DNA Repair Mechanisms .DNA Recombination Mechanisms .Chapter 14 The Techniques of Molecular Genetics .Basic Techniques Used to Identify, Amplify, and Clone Genes .DNA CLONING: AN OVERVIEW .Construction and Screening of DNA Libraries .The Molecular Analysis of DNA, RNA, and Protein .The Molecular Analysis of Genes and Chromosomes .Chapter 15 Genomics .Genomics: An Overview .Correlated Genetic, Cytological, and Physical Maps of Chromosomes .The Human Genome Project .RNA and Protein Assays of Genome Functions .Genome Diversity and Evolution .Chapter 16 Applications of Molecular Genetics .Use of Recombinant DNA Technology to Identify Human Genes and Diagnose Genetic Diseases .Human Gene Therapy .DNA Profiling .Production of Eukaryotic Proteins in Bacteria .Transgenic Animals and Plants .Processes by Inhibiting Gene Expression .Genome Engineering .Chapter 17 Regulation of Gene Expression in Prokaryotes .Strategies for Regulating Genes in Prokaryotes .Constitutive, Inducible, and Repressible Gene Expression .Positive and Negative Control of Gene Expression .Operons: Coordinately Regulated Units of Gene Expression .The lactose operon in E. coli: Induction and Catabolite Repression .The Tryptophan Operon in E. coli: Repression and Attenuation .Posttranscriptional Regulation of Gene Expression in Prokaryotes .Chapter 18 Regulation of Gene Expression in Eukaryotes .Ways of Regulating Eukaryotic Gene Expression: An Overview .Environmental and Biological Factors .Molecular Control of Transcription in Eukaryotes .Gene Expression and Chromatin Organization .Activation and Inactivation of Whole Chromosomes .Chapter 19 Inheritance of Complex Traits .Complex Traits .Statistics of Quantitative Genetics .Statistical Analysis of Quantitative Traits .Molecular Analysis of Complex Traits .Correlations between Relatives .Quantitative Genetics of Human Behavioral Traits .Chapter 20 Population Genetics .The Theory of Allele Frequencies .Natural Selection .Random Genetic Drift .Populations in Genetic Equilibrium .Chapter 21 (Online) Transposable Genetic Elements .Transposable Elements: An Overview .Transposable Elements in Bacteria .Cut–and–Paste Transposons in Eukaryotes .Transposon Activity in Maize .Retroviruses and Retrotransposons .Transposable Elements in Humans .The Genetic and Evolutionary Significance of Transposable Elements .Chapter 22 (Online) The Genetic Control of Animal Development .A Genetic Perspective on Development .Maternal Gene Activity in Development .Zygotic Gene Activity in Development .Genetic Analysis of Development in Vertebrates .Chapter 23 (Online) The Genetic Basis of Cancer .Cancer: A Genetic Disease .Oncogenes .Tumor Suppressor Genes .Genetic Pathways to Cancer .Chapter 24 (Online) Evolutionary Genetics .The Emergence of Evolutionary Theory .Genetic Variation in Natural Populations .Molecular Evolution .Speciation .Human Evolution .Appendices .Appendix A: The Rules of Probability .Appendix B: Binomial Probabilities .Appendix C: Evolutionary Rates .Answers to Odd–Numbered Questions and Problems .Glossary .Index
- ISBN: 978-1-118-87589-6
- Editorial: John Wiley & Sons
- Encuadernacion: Rústica
- Páginas: 648
- Fecha Publicación: 06/11/2015
- Nº Volúmenes: 1
- Idioma: Inglés