Advances in Transition-Metal Mediated Heterocyclic Synthesis

Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals (palladium, platinum, rhodium, ruthenium, copper, iron and gold) to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the Heterocyclic systems (mainly aza- and oxa-heterocycles). As such, it covers recent applications on the synthesis of heterocycles, also describing the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction). Chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalyzed by other metals (Rh, Ru, Co). Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, the contents of this book are extremely helpful, not only for chemists mainly focused on synthesis, but also for those interested in reaction mechanisms involving transition metals. Helpfully organized by transformation type to stimulate the search for new synthetic processesCompletely illustrated and written by global expertsIncludes thoughtfully selected strategies chosen by the editors to exemplify the state-of-the-art of the subject, including transition-metal reactions involving unsaturated systems, organopalladium chemistry, and metal-catalyzed C-H activation INDICE: 1. New Transition Metal-Catalyzed Annulations Involving Allenes2. Novel Gold(I)-Catalyzed Cyclization Reactions Towards the Synthesis of Aza- and Oxaheterocycles3. Iron-Catalyzed Prins Reactions Towards the Synthesis of Oxaheterocycles4. Synthesis of Heterocycles Through Transition Metal-Catalyzed Isomerization Involving Metathesis Reactions5. Synthesis of Heterocycles by Palladium-Catalyzed Carbonylative Reactions6. Synthesis of Heterocycles by Palladium-Catalyzed Arylation and Alkenylation of C(sp3)-H Bonds7. Palladium-Catalyzed C-H Activation of Aliphatic Amines to Give Strained Heterocycles8. Synthesis of Heterocycles by Palladium-Catalyzed Coupling Reactions Involving Tosylhydrazones9. Controlling the Selectivity in Intramolecular Palladium-Catalyzed Cyclization Reactions Towards the Synthesis of Heterocycles10. Synthesis of Heterocycles by C-H Bond Functionalization Based on Transition- Metal Carbene Migratory Insertion11.New Alkyne Annulations Catalyzed by Transition Metals (Ru, Co, .) Towards the Synthesis of Heterocycles

• ISBN: 978-0-12-811651-7
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 375
• Fecha Publicación: 01/06/2018
• Nº Volúmenes: 1
• Idioma: Inglés