This second edition of a successful title bridging toxicology and environmental chemistry adopts a unique approach that 'follows' chemicals on a molecularlevel, from the environment through the different uptake mechanisms into the body, to the toxic effect. Along the way, this textbook explains the differentroutes of degradation and metabolism of the different classes of chemicals, linking general chemical properties to their toxicological equivalents. All thechapters have been thoroughly updated and the contents signi cantly expanded,including for example new chapters on pesticides, food chemicals and pharmaceuticals, as well as sections discussing endocrine disruptors and carcinogenicity assays. This is an essential text for a wide audience ranging from pharmacologists to environmental chemists and toxicologists. INDICE: Chemicals and society The chemicals of life and nature Chemical properties Uptake, distribution and elimination of chemicals Metabolism of exogenous compounds in mammals Conversions and transformations in the environment Toxic effects of chemicals The molecular basis for genotoxicity and carcinogenicity Hazardous chemicals Environmental effects of chemicals
- ISBN: 978-3-527-32582-5
- Editorial: John Wiley & Sons
- Encuadernacion: Rústica
- Páginas: 413
- Fecha Publicación: 12/05/2010
- Nº Volúmenes: 1
- Idioma: Inglés