The Human Hypothalamus: Middle and Posterior Region

The Hypothalamus is an important area of the brain for understanding a variety of neurological disorders. This volume summarizes for readers the anatomy and physiology of the middle and posterior hypothalamus, to better understand pathology and treatment of hypothalamus related disorders. In addition to anatomy and physiology in humans, cytoarchitecture and chemoarchitecture in rodents is provided. The volume explores the role of the hypothalamus in disorders of eating, sleeping, anxiety, and mood, as well as its role in sexual behavior and gender identity. Coverage includes how Parkinson's, Alzheimer's and other neurological disorders relate to the hypothalamus. Reviews the anatomy and physiology of the middle and posterior hypothalmusProvides cytoarchitecture and chemoarchitecture from rodentsDiscusses hypothalamic related disorders of eating, sleeping, anxiety, and moodCovers how Parkinson's, Alzheimer's and other neurological disorders relate to the hypothalamusExplores the role of the hypothalamus in sexual behavior and gender identity INDICE: Section 1: Ventromedial nucleus (VMN; nucleus of Cajal) and Dorsomedial nucleus (DMN) 1 DBS of VMN and DMN, appetite disorders, sexual behavior and panic attacks 2 DMN/VMN and sympathetic outflow Section 2: Infundibular nucleus (INF) 3. The Kisspeptin system, its co-transmitters, its relationship with GnRH and NKB, its role in the physiology of reproduction and changes with age 4. Kisspeptin in the integration of sexual and emotional brain processing 5. The physiology of menopause and their implications 6. The Neurokinin B system in relation to sex and gender-identity 7. Gonadotropin releasing neurons and tanycytes in the infundibular nucleus and median eminence 8. The role of  Melanocortins, AgRP, NPY and VGF in food reward, overeating, obesity and diabetes 9. Hypothalamic melanocortin pathway and weight loss in ALS Section 3: Lateral tuberal nucleus (NTL) 10. Cytoarchitecture, chemoarchitecture and homology with the rodent PV1 nucleus Section 4: Lateral hypothalamic area (LHA), perifornical area 11. The orexin/ hypocretin system alterations in neuropsychiatric disorders: relation to signs and symptoms 12. Relation between orexin expression and opiates 13. Orexin receptor antagonists for sleeping disorders and narcolepsy 14. Animal models orexin/hypocretin deficiency Section 5: Tuberomamillary complex 15. Histamine receptors, agonists and antagonists in health and disease 16. The Tuberomamillary Nucleus in neuropsychiatric disorders 17. The Tuberomamillary Nucleus in Narcolepy- Cataplexy 18. Animal models Section 6: Subthalamic nucleus (STN) 19. High resolution of the STN in relation to its topographical, chemical organization of the STN 20. The STN limbic functions and impulse control 21. DBS in the STN for different neuropsychiatric disorders  and their side effects 22. The STN and placebo effects in Parkinson Section 7: Corpora mamillaria (CM), fornix, mamillo-thalamic tract 23. Functional neuroanatomy and tractography (DTI of mamillo-thalamic tract, Medial mamillary nucleus, Lateral mamillary nucleus (nucleus intercallatus, Fornix Mamillo-thalamic tract, (Vicq d'Azyr) 24. DBS of the fornix for mild AD, Parkinson and other disorders 25. Wernicke encephalopathy and Korsakoff syndrome Section 8: Circumventricular organs: Organum vasulosum lamina terminalis 26. MRI and functional anatomy of the circumventricular organs 27. Organum vasulosum lamina terminalis functional changes during thirst and drinking in humans 28. Microscopic anatomy of the lamina terminalis and microsurgical third ventriculostomy Section 9: Olfactory system 29.  The development of the human vomeronasal organ (Jacobson's organ) and pherormones 30. Pherormone effects on the human hypothalamus in relation to sexual orientation and gender 31. Kallman syndrome: semaphorin and other mutations and GnRH migration 32. Olfactory processing in schizophrenia, bipolar disorder, major depression and anxiety 33. Olfactory dysfunction as an early marker of Parkinson's disease and Alzheimer's disease

• ISBN: 978-0-12-820107-7
• Editorial: Elsevier
• Encuadernacion: Cartoné
• Páginas: 807
• Fecha Publicación: 01/08/2021
• Nº Volúmenes: 1
• Idioma: Inglés