The biochemistry of drug metabolism [v. 2] Conjugations, consequences of metabolism, influencing factors

The biochemistry of drug metabolism [v. 2] Conjugations, consequences of metabolism, influencing factors

Testa, Bernard
Krämer, Stefanie D.

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Volume Two contains the last four parts of this work. Part 4 is devoted to the huge field of conjugation reactions, with much information being given on transferases. As in the two preceding parts, each drug-metabolizing enzyme or enzyme family begins with an Enzyme Identity Card summarizing its nomenclature and biochemical essentials. The reactions examined here include methylation, sulfation, glucuronidation, acetylation, conjugation with glutathione, while there is also a rigorous presentation of the pivotal role of xenobiotic-coenzyme A conjugates as a crossroads to various metabolic reactions INDICE: Reactions of conjugation and their enzymes. Metabolism and bioactivity. Etc...

  • ISBN: 978-3-906390-54-3
  • Editorial: Wiley-VCH
  • Encuadernacion: Rústica
  • Páginas: 588
  • Fecha Publicación: 01/10/2010
  • Nº Volúmenes: 1
  • Idioma: Inglés