Biologically Active Peptides: From Basic Science to Applications for Human Health

Biologically Active Peptides: From Basic Science to Applications for Human Health stands as a comprehensive resource on bioactive peptide science and medicine. With contributions from more than thirty global experts, topics discussed include bioactive peptide science, structure-activity relationships, best practices for their study and production, and applications in medicine. In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and production. Methods and technology-driven chapters offer step-by-step guidance in peptide preparation from different source materials, bioactivity assays, analysis and identification of bioactive peptides, encoding bioactive peptides. Later, applications across disease areas and medical specialties are examined in-depth, including the use of bioactive peptides in treating obesity, diabetes, osteoporosis, mental health disorders, food allergies, and joint health, among other disorders, as well as bioactive peptides for sensory enhancement, sports and clinical nutrition, lowering cholesterol, improving cardiovascular health, and driving advances in biotechnology. Discusses the latest advances in bioactive peptide chemistry, functionality and analysisOffers step-by-step instruction in applying new technologies for peptide extraction, protection, production and encoding, as well as employing bioactive peptide sequencing and bioactivity assays in new researchEffectively links basic peptide chemistry, human biology and diseaseFeatures chapter contributions from international experts across disciplines and applications INDICE: 1. Overview of bioactive peptides in health and disease2. Enzymatic mechanisms for generation of bioactive peptides3. Methodologies for extraction and separation of bioactive peptides4. Methodologies for use of novel technologies in bioactive peptide preparation5. Methodologies for peptidomics identification and quantification6. Methodologies for bioactivity assay: Biochemical study7. Methodologies for bioactivity assay: Cell study8. Methodologies for bioactivity assay: Animal study9. Methodologies for bioactivity assay: Human study10. Methodologies for bioavailability assessment11. Methodologies for study of Structure and function12. Methodologies for study of Mechanisms of action: Biochemistry approach13. Methodologies for study of Mechanisms of action: Multi-omic approach14. Methodologies for study of Mechanisms of action: Gene editing approach15. Databases on bioactive peptides sequences16. Technologies for bioactive peptides protection and delivery17. Sources of bioactive peptides18. Applications in nutrition: Mineral-binding19. Applications in nutrition: Clinical nutrition20. Applications in nutrition: Sport nutrition21. Applications in nutrition: Cholesterol lowering22. Applications in nutrition: Sensory enhancer (umami peptides and others)23. Applications in medicine: Cardiovascular benefit (ACE inhibitory, antioxidant and antiinflammatory peptides)24. Applications in medicine: Diabetes prevention (hypoglucemic peptides, DPP IV inhibitory25. Applications in medicine: Obesity (including satiety control)26. Applications in medicine: Osteoporosis27. Applications in medicine: Mental health28. Applications in medicine: Food allergy29. Applications in medicine: Joint health30. Applications in biotechnology: Cloning and expression of synthetic genes encoding bioactive peptides

• ISBN: 978-0-12-821389-6
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 512
• Fecha Publicación: 01/06/2021
• Nº Volúmenes: 1
• Idioma: Inglés