Visual transduction and non-Visual light perception

Remarkable advances have contributed to revolutionizing the study of vertebrate vision. The first step to identifying objects and establishing spatial relationships is the visual transduction cascade, a process that underpins a wide range of ocular diseases and therapies. Toward that, The Visual Transduction Cascade: Basic and Clinical Principles reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules (such as transducins, phosphodiesterases, and CyclicGMP metabolizing enzymes) operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing readiation outside of the visible wavelengths - a good example of the limitations of the human sensory systems. Thorough explication of the phototransduction cascade Comprehensive and multidisciplinary Covers developmental, structural and molecular mechanisms Leads to amore exhaustive understanding of ocular diseases and therapies INDICE: From the contents An Organ of Exquisite Perfection.- Development of the Foveal Specialization.- Contribution of Environmental Factors to Rod Photoreceptor Development.- Photoreceptor-RPE Interactions: Physiology and Molecular Mechanisms.- Molecular Biology of IRBP and its Role in the Visual Cycle.- Regulation of Photoresponses by Phosphorylation.- The cGMP Signaling Pathway in Retinal Photoreceptors and the Central Role of Photoreceptor Phosphodiesterase (PDE6).- Rhodopsin Structure, Function, and Involvement in Retinitis Pigmentosa.- Multiple Signaling Pathways Govern Calcium Homeostasis In Photoreceptor Inner Segments.- The Transduction Channels of Rod and Cone Photoreceptors.- Rhodopsins in Drosophila Color Vision.- INAD Signalling Complex of Drosophila Photoreceptors.- Visual Signal Processing in the Inner Retina.- Human conespectral sensitivities and color vision deficiencies.- Luminous Efficiency Functions.- Cone Pigments and Vision in the Mouse.

• ISBN: 978-1-58829-957-4
• Editorial: Humana Press
• Encuadernacion: Cartoné
• Páginas: 509
• Fecha Publicación: 01/06/2008
• Nº Volúmenes: 1
• Idioma: Inglés