This completely updated and expanded second edition of Systemic Lupus Erythematosus; Basic, Applied and Clinical Aspects includes topics not covered previously with contributors who are at the forefront of each specific topic and with a global appeal. Each chapter will be short and will be presented critically and not in an encyclopedic manner and with selected, up to 50, references which should be valuable to a wider audience. As a seasoned (not old) editor, he worked with practically all the contributors and this enables to achieve the goals of the book. This manual to SLE combines basic science with clinical science to provide a translational treatment of the disease. Systemic Lupus Erythematosus, a Manual, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries. This new edition includes new chapters on: Microbiota and lupus by Dr. Greg Silverman- a pioneer on this topicInnate immune cells and lupus Monogenic lupus And includes also new techniques and ideas that have been developed for the study of the SLE process and related conform all invariant systems like couplings with Gaussian fields and the related geometries, measures on loops, and new perspectives on CFT. Distills current understanding of the cellular, molecular, genetic and environmental factors that instigate and drive the diseaseIncludes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and moreConveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damageDiscusses the latest treatment options on disease modifying or disease controlling agentsProvides 'one stop' coverage of all the latest scientific and clinical developments in SLE: new concepts in epidemiology, disease activity measures and outcomes; new concepts in immunoregulation, genetic and pathogenic mechanisms; new understanding and novel presentation of the processes of tissue/organ damage; comprehensive coverage of clinical features; and the very latest concepts in treatment INDICE: A. Epidemiology and Diagnosis B. Pathogenesis C. Mechanisms of tissue damageD. Clinical aspects of the diseaseE. Antiphospholipid SyndromeF. Treatment of the disease
- ISBN: 978-0-12-814551-7
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 660
- Fecha Publicación: 01/04/2020
- Nº Volúmenes: 1
- Idioma: Inglés