Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology

Progress in Molecular Biology and Translational Science, Volume 166, provides the most topical, informative and exciting monographs available on a wide variety of research topics related to Dancing protein clouds, Intrinsically disordered proteins in the norm and pathology. The series includes in-depth knowledge on molecular biological aspects of organismal physiology, along with insights on how this knowledge may be applied to understand and ameliorate human disease. Includes comprehensive coverage of molecular biologyPresents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information providedContains contributions from renowned experts in the field INDICE: 1. Protein intrinsic disorder and structure-function continnum Vladimir N. Uversky 2. Intrinsic disorder associated with 14-3-3 proteins and their partners Nikolai N. Sluchanko 3. Intrinsically Disordered Proteins and Phenotypic Switching in Cancer: The Role of Conformational Dynamics Prakash Kulkarni 4. Translational diffusion of flexible molecules Irina Nesmelova 5. Disorder-to-Order Transition During Amyloid Formation Samrat Mukhopadhyay 6. Impacts of Mitochondrial Dysfunction and Oxidative Stress on Intrinsically Disordered Proteins in Alzheimer´s and Parkinson´s Disease Pathologies Orkid Coskuner 7. Shear-Induced Amyloid Formation of IDPs in the Brain Conrad N. Trumbore 8. Roles of intrinsic disorder in sarcomere formation and function Dmitri Tolkatchev and Alla S. Kostyukova 9. Computational prediction of functions of intrinsically disordered regions Lukasz Kurgan 10. The Balance between Liquid-Liquid Phase Separation and Fibrillization in Neurodegenerative Diseases Benjamin Wolozin 11. Involvement of intrinsically disordered proteins in mechanism of viral pathogenesis and control Rajanish Giri

• ISBN: 978-0-12-816851-6
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 300
• Fecha Publicación: 01/09/2019
• Nº Volúmenes: 1
• Idioma: Inglés