Fundamentals of Biochemistry: Life at the Molecular Level, Transparency Acetates, 2nd Edition

Description This text uses a more brief and qualitative approach to present biochemistry with chemical rigor, focusing on the structures of biomolecules, chemical mechanisms, and evolutionary relationships. It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries. This edition has been thoroughly updated to reflect the most recent advances in biochemistry, particularly in the areas of genomics and structural biology. A new chapter focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry. New to This Edition New subtitle reinforces the importance and relevance of the chemistry of life. A new chapter (28) focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry. Pathways of Discovery boxes highlight the lives and work of key researchers who made significant advances in biochemistry. Linus Pauling (the author, Don Voet’s original teacher from Cal Tech), Francis Collins (cystic fibrosis gene), Rosalind Frankin (structure of DNA), Max Perutz (structure and function of hemoglobin) are highlighted, among others. Bioinformatics Exercises – applicable to chapters 3, 5, 6, 12, 13 - provided at the back of the book, are designed for classroom, laboratory, or independent study – and provide background information and instructions for exploring molecular sequences, protein structure, metabolic pathways, and molecular diseases. These exercises introduce the techniques of bioinformatics that involve the use of computers, internet-accessible databases, and tools that have been developed to mine those databases. An answer key is provided. The section on Metabolism (Part Four) includes new insights provided by advances in bioinformatics. In the final section of the text, Part Five: “Replication and Gene Expression,” the chapters on DNA structure, replication, DNA repair, transcription, and protein synthesis places emphasis upon the essential biochemical, rather than biological, aspects of these processes. New problems have been added to the end of each chapter in the text. Additional sample calculations provide step-by-step skill building exercises in underlying chemical and computational aspects of the course. The Student Companion has been expanded and revised. Upgraded and re-designed web-based media program to accompany and complement the text includes Interactive Exercises, Guided Explorations, Animated Figures, as well as Kinemages. Media resources have been upgraded to take advantage of the most recent, web-friendly 3D visualization tools, eliminating the need for the Chime plug-in, which has proven to be problematic.

• ISBN: 978-0-471-21511-0
• Editorial: JOHN WILEY & SONS, LTD.(2ª)
• Encuadernacion: Rústica
• Fecha Publicación: 01/11/2013
• Nº Volúmenes: 1
• Idioma: