While new insights into the mechanisms and the treatment of stroke have been obtained from animal experiments over the past several years, this is the first book in more than two decades to compile research in this essential area. Calling on a group of cutting-edge researchers, it offers detailed explanations of the methods and techniques for accomplishing different stroke models in rats. As of now, no specific neuroprotective treatment for ischemic stroke is available. This book provides a starting point for those researchers employing stroke models to develop new drugs to counteract this problem. INDICE: Statistical Update for Stroke in America. Rationale for using Stroke Models. Animal Models to Induce Focal Stroke: A Historical Survey. Anatomy and Cerebral Circulation of the Rat. Which Animal to Choose? Which Model to Use? Anesthesia of Rat during Stroke Surgery. Surgery on Animals. Postoperative Care. Comparison of Different Focal Stroke Models. Outcome Check. Total Wisdomfrom Failure: Reasons Why Neuroprotective Therapies that Work in the Laboratory Fail in Clinical Trials. Sampling on Stroke Rats. Administration of Compound. Common Bio-Physiological Data in Rodents.
- ISBN: 978-0-8493-9578-9
- Editorial: CRC Press
- Encuadernacion: Rústica
- Páginas: 432
- Fecha Publicación: 01/08/2008
- Nº Volúmenes: 1
- Idioma: Inglés