Management of chemical and biological samples forscreening applications

Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screeningcenters in the pharmaceutical and biotechnological field. It spans the entirefield of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program. INDICE: AN INTRODUCTION TO SAMPLE MANAGEMENT What is Sample Management? QUALITY IN COMPOUND MANAGEMENT Generating a High Quality Compound Collection Assessing Compound Quality Maintaining and Delivering Quality with Compound Management Obtaining and Maintaining High Quality Tissue Samples: Scientific and Technical Considerations for Evidence Based Practice EFFICIENT SAMPLE MANAGEMENTPROCESS The Lean Sample Management Laboratory SAMPLE/COMPOUND LOGISTICS Sample Distribution AUTOMATION IN COMPOUND MANAGEMENT Development of Automation in Sample Management Acoustic Technology Large Scale Automated Storage and Retrieval of Biological Samples at -80?C INFORMATION TECHNOLOGY Information Technology Systems for Sample Management BIOBANKING Managing the American Tissue Culture Collection: The Global Bioresource Center Establishing a Tissue Biobank FUTURE PERSPECITVES What does an HTS File of the Future Look Like? The Impact of Future Technologies within Biobanking Outsourcing Sample Management

• ISBN: 978-3-527-32822-2
• Editorial: Wiley-VCH
• Encuadernacion: Cartoné
• Páginas: 424
• Fecha Publicación: 22/02/2012
• Nº Volúmenes: 1
• Idioma: Inglés