Microbial Biofilms: Role in Human Infectious Diseases

Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanism. In addition, due to close proximity of microbes within biofilms, increase genetic transformation has been detected results in increases frequency of antibiotic gene spread. With the advancement in science and technology, novel strategies and been proposed to combat the impact of biofilms on human health. Microbial biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection/and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms and the burden of biofilm associated infections. In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants. Fulfils the knowledge gap in biofilm study Focuses on new and emerging concepts in microbial biofilm research Highlights the various anti-biofilm strategies Provides concise, thorough, and up-to-date information about the important role of microbial biofilms in human diseases INDICE: 1. Bacterial Biofilms and infectious disease in human health: a concise review 2. Microbial biofilms: Role of biofilms in recurrent orthopaedic infections 3. Dental biofilms: Application of nanoparticles to combat biofilms 4. Streptococcus biofilms, and their role in human infectious diseases 5. Surface coating: Strategy to prevent bacteria adhesion on medical implants 6. Bacterial biofilm a major challenge in medical indwelling devices 7. Single-species and multi-species biofilms causing infections 8. Effects of environmental factors to promote formation of biofilms by respiratory pathogens 9. Gut Microbiota: Role of biofilms in human health 10. Antimicrobial/antibiotic resistance of biofilms and factors contributing to resistance 11. Cell to cell interaction and cell signalling in biofilms 12. Microbial biofilms and the skin microbiome 13. Synthetic and phyto-compounds to combat microbial biofilms 14. Next generation sequencing: Role in microbial biofilms study

• ISBN: 978-0-443-19252-4
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 350
• Fecha Publicación: 01/08/2023
• Nº Volúmenes: 1
• Idioma: Inglés