Iron deficiency and overload: from basic biology to clinical medicine

Iron deficiency is ever-present among all populations throughout the world irrespective of race, culture, or ethnic background. Even with the latest advances in medicine, improved nutrition, and the ready availability of cheap oral iron, there is still no satisfactory explanation for the widespread occurrence of iron deficiency or for the absence of an effective treatment. Iron Deficiency and Overload: From Biology to Clinical Medicine is an important new text that provides a timely review of the latest science concerning iron metabolism as well as practical, data-driven options to manage at-risk populations with the best accepted therapeutic nutritional interventions. Chapter topics reflect the excitement in current theoretical development and laboratory activity in this area. Includes public health concerns Examines behavioral effects Central nervous system disorders and treatment INDICE: From the contents The cellular physiology of iron.- Regulation of iron absorption and distribution.- The role of hepcidin in iron homeostasis.- Iron as nutrient: Strategies for iron acquisition and usage by pathogenic microorganisms.- Iron as a drug and drug-drug interactions.- Iron Deficiency and Excess in the brain: Implications for Cognitive Impairment and Neurodegeneration.- Brain iron deposition in aging and disease: Role of HO-1.- Iron Deficiencyand Neuropharmacology.- Peripheral effects of Iron Deficiency.- Iron Metabolism in neurons of the motor systems of the central nervous system: Lessons fromIron Deficiency and Overloading pathologies.- Learning. Memory and Cognitive functioning.- Stress, Immunology and Cytokines.- MRI of brain iron and Neurodegenerative diseases: A Potential Biomarker.

• ISBN: 978-1-934115-22-0
• Editorial: Humana
• Encuadernacion: Cartoné
• Páginas: 470
• Fecha Publicación: 01/07/2009
• Nº Volúmenes: 1
• Idioma: Inglés