Multicomponent Reactions in Organic Synthesis

Comprehensive and up–to–date, this book focuses on the latest advances in the field, such as newly developed techniques, more environmentally benign processes, broadened scopes, and completely novel MCRs. In addition to carbene–promoted MCRs and frequently applied metal–catalyzed MCRs, it also covers recently developed catalytic enantioselective variants as well as MCR in drug discovery and for the synthesis of heterocyclic molecules and macrocycles. Edited by the leading experts and with a list of authors reading like a who?s who in multicomponent reaction chemistry, this is definitely a must–have for every synthetic organic chemist as well as medicinal chemists working in academia and pharmaceutical companies. INDICE: 1.) General Introduction on MCRs: Past, Present and Future 2.) Discovery of Novel MCRs 3.) Aryne–based MCRs 4.) Ugi–Smiles Reaction 5.) 1,3–Dicarbonyl in MCR 6.) Heterocycles in MCR 7.) Diazoacetate and Related Stable Carbene Species in MCRs 8.) Metal–catalyzed MCRs 9.) MCR in Drug Discovery 10.) MCRs for the Synthesis of Macrocycles 11.) MCR under Oxidative Conditions 12.) Allenes in Multicomponent Synthesis of Heterocycles 13.) Alkynes in Multicomponenet Synthesis of Heterocycles 14.) Cyclic Anhydrides in MCRs 15.) Radical Reaction in Multicomponent Reactions 16.) Catalytic Enantioselective MCRs

• ISBN: 978-3-527-33237-3
• Editorial: Wiley VCH
• Encuadernacion: Cartoné
• Páginas: 512
• Fecha Publicación: 17/12/2014
• Nº Volúmenes: 1
• Idioma: Inglés